Synthetic GLP1 used in obesity treatment can have a range of side effects, which vary depending on the medication. Orlistat commonly causes gastrointestinal issues such as diarrhea, flatulence, and bloating, with more serious risks including liver damage and kidney stones. Phentermine may lead to dry mouth, insomnia, increased heart rate, and elevated blood pressure, with the potential for heart palpitations and dependency. Liraglutide often causes nausea, vomiting, and diarrhea, while serious side effects include pancreatitis, thyroid tumors, and kidney problems. The combination drug Naltrexone/Bupropion can cause nausea, headaches, and insomnia, and carries risks of seizures, increased blood pressure, and psychiatric effects like mood swings.
Similarly, Semaglutide, just like liraglutide, can cause nausea, vomiting, and diarrhea, with serious risks including pancreatitis, thyroid tumors, and diabetic retinopathy. Topiramate may result in tingling sensations, dry mouth, dizziness, and cognitive issues, with serious side effects including an increased risk of birth defects.
Metformin, primarily used for Type 2 diabetes, also can cause gastrointestinal upset and, in rare cases, lactic acidosis and vitamin B12 deficiency.
Bariatric surgery medications, such as proton pump inhibitors and pain relievers, can lead to constipation, digestive issues, and nutrient deficiencies.
